The clinical symptoms of hepatitis B infection vary greatly depending on the stage of infection, age and underlying conditions, as follows: 1. The milder ones do not have any special symptoms, and most of them are found to be positive for hepatitis B serological markers only through physical examination, or elevated transaminases during liver function tests; 2. Some of them have non-specific symptoms such as fatigue, low fever, loss of appetite, jaundice, skin itching, fullness, hidden pain in the upper abdomen or liver area Some patients with severe cirrhosis have spider nevi on their bodies, especially on the back of the chest and neck; some of them have redness between the fissures of the palms, called liver palms; 4. Men with severe disease have breast lumps and breast development; women with severe disease have menstrual disorders; those with liver failure are prone to petechiae, petechiae and changes in mental status.