The rate of infection after lumbar disc surgery is very low, but there are still postoperative infections,which should be given sufficient attention. Intervertebral space infection is one of the common complications after lumbar disc removal, and its clinical manifestations are different from general postoperative incision infection, and early diagnosis is difficult: even percutaneous puncture therapy between interventional surgery and non-surgical procedures may cause infection. The symptoms after infection are: 1. The patient’s postoperative symptoms of bright lumbar and leg pain are obviously reduced, and the situation is good in the short term, but intense lumbar pain and sciatica appear again 1-8 weeks after surgery, and the pain is different from that before surgery. Some patients may also show abdominal pain or lower abdominal radiating pain. 2. Muscle spasm of the low back is obvious, and the straight leg raising test is positive. There were no signs of infection in the surgical incision, but the local pressure pain was positive. The patient’s body temperature and pulse were normal. 3. The test puncture is usually not positive. The white blood cell count and classification are normal, but the blood sedimentation is significantly increased. Increased hematocrit is of great significance in the diagnosis of intervertebral infection. 4, early onset of the X-ray film no obvious abnormalities, 1-3 months after surgery can be seen in the adjacent intervertebral space narrowing, vertebral destruction, sclerosis, anterior and posterior edges of new bone formation of bone superfluous, and eventually fusion of adjacent vertebral body. 5. Feeling severe pain in the lumbar region, not daring to turn over, not daring to move, and having low fever and accelerated blood sedimentation. When intervertebral infection occurs, prompt treatment should be given according to the following principles: 1. systemic application of antibiotics and continue for more than 6 weeks. 2.If necessary, lesion removal and drainage should be performed to control the infection. 3.The patient’s low back should be strictly braked for 4-8 weeks, and skin traction of both lower limbs can also be used. 4, must limit lumbar activities, the application of antimicrobial therapy, most patients can control the infection. Infected vertebral space adjacent to the vertebral body can generally reach bony fusion in 3-4 months, and the symptoms can be reduced or disappear after fusion. Patients should actively cooperate with treatment during lumbar back braking to prevent further spread of inflammation and early fusion of the vertebral body. It takes about 1-2 years after conservative treatment to achieve complete bony fusion between the vertebrae and complete disappearance of symptoms. If the infection is serious and conservative treatment is ineffective, it is necessary to consider the original incision into the lesioned vertebral space, remove the infection, necrotic tissue and its secretions, perform irrigation and flushing, select appropriate antibacterial agents, and make negative pressure drainage. Alternatively, the incision may not be sutured or opened for drainage, and then sutured in the second phase after the infection is controlled. Therefore, patients who have just undergone lumbar disc herniation surgery must pay special attention to prevent infection. Once the intervertebral space infection occurs, it should be treated promptly and properly.