In general, untreated patients with lighter forms of the disease live longer, while heavy forms have a poor prognosis, e.g., type I heavy patients tend to die within 10 years of age, and type II heavy patients also live for more than 10 years. Prenatal diagnosis is required for families at high risk of prevalence to prevent further births in the same family. Newborn screening methods for the disease are currently under study, and it is expected that with mature experience and ethical refinement, the disease will also be diagnosed before its onset and treated before the onset of obvious symptoms by means of newborn screening. With the exception of type II, mucopolysaccharide storage disorders are autosomal recessive disorders. When parents are told that their child has a hereditary disease, the first question they ask is how can this disease be hereditary when there is no such child in my family or in my spouse’s family? A disease that has direct genetic involvement is a genetic disease. If the parents have a disease in one generation and the child has the same disease, then it is called a dominant genetic disease; if the child has the disease because the parents do not have the disease and are carriers of the disease-causing gene, then it is called a recessive genetic disease. The family has a 25% chance of having another child with the same disease. 25% is a very high risk and it is important to have prenatal testing for the disease at a hospital that is qualified to diagnose it, not just the usual Down’s syndrome screening. If you have previously had a child with mucopolysaccharide storage disorder and need to get pregnant again, be sure to get tested.