The difference between plantar warts and corns is mainly manifested in the cause of the disease, hairy parts, clinical manifestations, treatment and other aspects. 1. The cause: plantar warts are mainly caused by human papilloma virus infection, while corns are mainly due to long-term friction and extrusion of the foot skin, and the formation of hard conical keratotic hyperplasia. 2. Happening parts: metatarsal warts can occur in all parts of the soles of the feet, while corns are mainly in the soles of the feet between the toes, the back of the toes, the outer side of the little toe and other long-term friction and pressure parts. 3. Clinical manifestations: metatarsal warts are initially smooth papules, gray-brown or yellow-brown, and then gradually become rough, after removing the surface of the keratin, you can see a “soft core”, but also brown or black hemorrhage points. Corns, on the other hand, are yellowish or dark yellow in color. If the surface keratin is removed, a keratin plug shaped like a corns can be seen; in severe cases, it is painful and affects the patient’s ability to walk. 4. Treatment: metatarsal warts are usually treated with laser therapy, photodynamic therapy and other physical modalities, as well as topical retinoids, fluorouracil cream and other medications as prescribed by the doctor. The two are different diseases, and a differential diagnosis is usually required when patients seek treatment. It is recommended that when patients have suspected symptoms, they should consult a doctor in time for examination, and under the guidance of the doctor to make a clear diagnosis, and then carry out the appropriate treatment.