Alzheimer’s disease is a progressive neurodegenerative disease that often occurs in the elderly population, with Alzheimer’s disease being the most common, followed by vascular dementia and then mixed dementia. Its drug treatment, mainly includes the following. (1) Basic supportive therapy: including vasodilatation, improvement of cerebral circulation, nerve nutrition, antioxidant drugs, etc. Commonly used drugs include ginkgo biloba preparations, olanzapine, aniracetam, vitamin E, etc. (2) Drugs to improve cognitive function: ①Cholinesterase inhibitors: such as donepezil, lisdexamfetamine, carboplatin, galantamine, staphylocarpine A, etc. These drugs can reduce the degradation of acetylcholine and can play a certain role in improving the cognitive function of patients; ②NMDA receptor antagonists: commonly used in patients with severe Alzheimer’s disease, the representative drug is meperidine. (3) Control of psychiatric symptoms: Many patients will have hallucinations, delusions, depression, anxiety, sleep disorders and other psychiatric symptoms during the course of the disease. Antidepressants are often chosen from fluoxetine, paroxetine, citalopram, sertraline, etc.; antipsychotics are commonly used such as risperidone, olanzapine, quetiapine, etc. The choice of drugs to control psychiatric symptoms is: low dose start, slow increment, slightly longer interval between increments, minimum effective dose for short term use, attention to drug interactions, individualization, etc. Therefore, it is important to consult a neurologist and follow medical advice when using medication. In summary, the drug treatment for Alzheimer’s disease mainly includes the above, but patients must use the drugs individually under the guidance of doctors.