Mole tattooing and natural moles are formed by different factors, and are affected by the tattoo artist’s technique, and are different from natural moles in terms of appearance. Mole tattoo is mainly through the tattoo needle, the plant pigment quickly and evenly injected into the dermis layer under the surface of the skin, artificially creating implantable tattoos, so that the local area of the skin coloring, showing the desired color and style. Natural moles are caused by the abnormal proliferation of melanocytes in the skin, due to the collection of melanocytes in the body in the surface layer of the skin, with the growth of the body, there may be a localized slight bulge. Mole tattooing is the pursuit of skin personality by beauty lovers, it is a late external change, different from the natural formation of moles, if there is a need for mole tattooing, tattooing is an invasive operation, it is recommended to go to a regular medical institution to operate, so as to avoid cross infection caused by disinfection is not in place.