Respiratory viral infections are closely related to bronchial asthma, and it can induce wheezing and worsen clinical symptoms in many asthmatic patients. Viruses that cause wheezing: 1. Respiratory syncytial virus: the most common cause of wheezing in infants and children. 2.Rhinovirus: usually causes the common cold and is the main trigger for asthma in older children and adults. 3.Other respiratory viruses: such as parainfluenza virus, influenza virus, adenovirus and coronavirus, can also aggravate the symptoms of asthma. Mechanisms of respiratory infection-induced asthma: 1. destruction of airway epithelial cells; 2. stimulation of the production of virus-specific IgE antibodies; 3. promotion of the release of inflammatory mediators; 4. viral infection as an adjuvant of the inflammatory response: 5. recent studies have shown that some viruses can also cause acetylcholine release by stimulating the vagus nerve, leading to asthma exacerbation. The principles of treatment for acute exacerbation of asthma related to respiratory tract infection are the same as for other types of asthma, with inhaled rapid-acting beta2 agonists (SABA), and the dose of inhaled glucocorticoids (ICS) can be increased 2-4 times. Since asthma symptoms can persist for several weeks after the disappearance of the respiratory tract infection, anti-inflammatory therapy should be continued until asthma symptoms are completely controlled. The therapeutic value of macrolide antibiotics also needs to be further investigated because the role of chronic Mycoplasma pneumoniae and Chlamydia pneumoniae infection in the development of asthma and in promoting exacerbation of asthma symptoms has not been established.