The stomach presents with fasting pain, which in clinical practice may be acute or chronic superficial gastritis, acute or chronic erosive gastritis, or duodenal bulb ulcer, the most common being duodenal bulb ulcer, most often presenting with fasting stomach pain. In clinical peptic ulcers include gastric ulcers and duodenal ulcers, gastric ulcers occur in the ulcerated stomach and appear as postprandial pain. Duodenal bulb ulcers, which occur in the duodenal bulb due to ulcers, are more common in young people and are mainly caused by Helicobacter pylori infection, poor living and eating habits, and high gastric acid pain on an empty stomach, which can be relieved after eating. Gastroscopy is needed to make a clear diagnosis of duodenal bulb ulcer, and the treatment is to change the bad life and diet habits, avoid eating too spicy and stimulating food, avoid staying up late, and use anti-H. pylori triple or quadruple drugs, two courses of treatment can be cured.