The main complications of severe infection, also called severe sepsis, include the dysfunction and failure of various important organs, including respiratory failure, which is judged mainly by the oxygenation index below 300, and after reasonable oxygen therapy or an active oxygen administration program, the state of hypoxia cannot be corrected. The second is shock, also called circulatory failure, sepsis after adequate fluid resuscitation, but still can not correct the state of shock hypotension, secondary to poor tissue perfusion or even lactic acidosis is also called circulatory failure. Then the third complication may be renal failure, also called acute kidney injury, often manifested by acute oliguria, the hourly urine volume of this type of patients will often be less than 0.5 ml/h, and this process lasts not less than 2 hours, and then there may be a combination of some acute azotemia or creatinine elevation. Then the fourth may appear the performance of liver failure, often this kind of patients will show elevated transaminases, elevated bilirubin, these indicators are often higher than our chronic hepatitis patients his indicators will be more high, may be transaminases will soar to thousands or even tens of thousands may exist or even measured performance, and then often these patients with severe sepsis, very typical performance may exist the consciousness of If this impairment of consciousness does not awaken for a long time, it may be judged that there is brain failure, which is also called septic encephalopathy in medicine, and if these patients do not wake up within 1 week, they may wake up in about 4 weeks of the disease, that is, 1 month, and if they do not wake up in more than 4 weeks, they may be transferred to a state of permanent brain damage, and other Other common complications may include metabolic dysfunction and gastrointestinal dysfunction.