The medications used to treat H. pylori are three types of drugs: antibiotics, proton pump inhibitors, and bismuth, such as amoxicillin, clarithromycin, omeprazole, and bismuth potassium citrate. Currently, quadruple therapy is recommended for the treatment of H. pylori infection, i.e., two antibiotics, a proton pump inhibitor, and a bismuth agent. Commonly used antibiotics are amoxicillin, clarithromycin, metronidazole, tetracycline, furazolidone, etc. Pick two of these antibiotics. Commonly used proton pump inhibitors are omeprazole, lansoprazole, rabeprazole, pantoprazole, etc. Pick one of these proton pump inhibitors. Commonly used bismuth agents are bismuth potassium citrate and bismuth pectin. Quadruple therapy requires that all four medications be taken at the same time and that they be taken regularly and without interruption, with no breaks or omissions in the middle. Adverse reactions such as abdominal pain, diarrhea, nausea, and vomiting may occur after taking these medications, in addition to the black color of the stool after taking bismuth. If you have Helicobacter pylori infection, it is recommended to go to a regular hospital for consultation and standardized anti-Helicobacter pylori treatment under the guidance of a professional doctor, and avoid taking medication on your own.