Toe warts are medically called plantar warts, which are benign growths caused by human papillomavirus infection of the skin mucous membranes, and commonly present as yellow-brown flat papules with pain. Skin changes are generally manifested in the soles of the feet with small, shiny papules, not itchy, this protuberance grows up can be the size of a soybean. With localized pressure and friction the skin will keratinize and form a yellowish or tawny rough patch, usually this raised small mass is surrounded by a thickened keratinous ring. Another important manifestation is pain. Because of external pressure and friction, it is easy to lead to nerve endings damage and pain, but also because of local repeated friction caused by skin infection. It needs to be disinfected in time, usually need to be rinsed with iodine or saline, and actively treated to avoid more serious local infection or nerve loss. If the toe warts, may have difficulty walking, need to improve the comfort of shoes to protect the warty local skin. Seek medical treatment promptly to avoid delaying the condition.