Drugs that can lower uric acid include drugs that inhibit uric acid synthesis (allopurinol, febuxostat) and drugs that promote uric acid excretion (probenecid, benzbromarone).
1. Inhibit uric acid synthesis drugs: common drugs are allopurinol and febuxostat, allopurinol common adverse drug reactions include rash, nausea, vomiting, etc., febuxostat is generally not used for non-clinical symptoms of hyperuricemia, the common adverse drug reactions include nausea, arthralgia and liver function abnormalities.
2. Promote uric acid excretion drugs: representative of the promotion of uric acid excretion drugs, including probenecid and benzbromarone, mainly through the inhibition of renal tubular reabsorption of uric acid to play a role in promoting uric acid excretion, taking such drugs should be a large amount of drinking water, and can also take sodium citrate, sodium bicarbonate and other drugs alkalinization of the urine.
Drugs need to be used under the guidance of a physician, it is recommended that patients with high blood uric acid to the relevant departments of regular hospitals to consult in detail.