Progesterone is a progesterone hormone secreted by the ovaries, and due to individual differences, the progesterone value varies from one pregnant woman to another at each stage. The 4th-5th week of pregnancy is in early pregnancy, and normally, the reference value of progesterone in the 4th-5th week of pregnancy is 20-96ng/mL. If the value of progesterone in early pregnancy is insufficient, you can consider luteal insufficiency, and you should take the appropriate medication according to the doctor’s diagnosis, such as progesterone capsules, use progesterone suppositories, or intramuscular progesterone injections according to the doctor’s prescription. Progesterone level is related to the outcome of early pregnancy. Serum progesterone level in women with embryonic abortion and ectopic pregnancy is significantly lower than that in patients with preterm abortion and normal early pregnancy. Progesterone in the range of 15-25ng/mL has a pregnancy outcome that is basically intrauterine, but is prone to early preterm abortion. With progesterone less than 15ng/mL, the pregnancy outcome is more likely to be ectopic pregnancy or indolent abortion. If the progesterone is more than 25ng/mL, the pregnancy outcome is mostly normal intrauterine pregnancy, and some of them have pre-eclampsia, but usually after supplementation of luteal function, the pregnancy outcome can be continued. In conclusion, close monitoring of progesterone indicators during pregnancy is particularly important and it is recommended to pay sufficient attention to it. When the progesterone in pregnant women decreases or there is vaginal bleeding, the possibility of pre-eclampsia is considered, and then you should go to the hospital for blood HCG test and gynecological ultrasound to determine whether the fetus is developing well.