Periodontal disease in addition to damage to the periodontal tissues caused by bleeding gums, bad breath, gums red and swollen, exposed roots, teeth deformation, loose, chewing weakness, etc. In addition, periodontal disease also seriously affects the health of the whole body. It also seriously affects the health of the whole body. Severe periodontitis patients periodontal pocket ulcers within the harm up to the size of the palm of the hand, equivalent to the oral cavity has a palm-sized long-term non-healing wounds, the normal human oral cavity has more than 300 kinds of microorganisms, saliva 108/ml, dental plaque 1011/g dry weight. There is no wound in the normal human oral cavity bacteria can not invade, if there is a palm-sized long-term non-healing wound will cause serious harm to the body. Cardiovascular and cerebrovascular diseases, preterm and low-birth-weight births, gastrointestinal diseases . , respiratory diseases, intracranial infections, arthritis, iridocyclitis, nephropathy, and dermatologic diseases have all been reported in association with periodontal disease.