Primary premature ejaculation twenty years is possible to cure, can be improved by drugs, psychotherapy, surgery. 1. Drug intervention: can be used externally with compound lidocaine cream, can prolong the ejaculation time. Dapoxetine hydrochloride can be taken orally, the pharmacological mechanism involves central ejaculation regulation, for the sympathetic excitability of high central primary premature ejaculation patients with precise efficacy, fast-acting. All the above drugs need to pay attention to the side effects and adverse reactions, please use the above drugs under the guidance of a doctor. 2. Psychological therapy: enhance self-confidence, eliminate anxiety about sexual intercourse, learn sexual skills, serious cases can consult a professional psychological organization for psychological guidance. 3. Surgery: The commonly used surgical method is dorsal penile nerve selective amputation to reduce the sensitivity of the penis. However, the surgery is after all an invasive treatment, and there may be a series of complications and risks after the surgery. Surgery can be used as an adjunctive method of treating primary premature ejaculation, but it should not be used as a regular treatment option for primary premature ejaculation. Patients with primary premature ejaculation are advised to go to the hospital in time for treatment under the guidance of a doctor.