Wake up in the middle of the night panic like death may be nightmares, myocardial infarction, asthma attack, vegetative nerve disorders, hypoglycemia and other reasons. 1. Nightmare: in the middle of the night sleep may have nightmares lead to excessive body shock, sympathetic over-excitement and heart rate significantly accelerated, so this symptom appears. 2. Myocardial infarction: Coronary artery spasm, embolism, atherosclerosis and other causes of lumen blockage, myocardial ischemia and infarction, pain in the precordial area, chest tightness, panic, shortness of breath and other symptoms. 3. Asthma attack: asthma attack in the middle of the night during sleep, lung ventilation is severely restricted, myocardium and other tissues are lacking oxygen, so the heart will beat faster, panic. 4. Plant nervous disorders: Sympathetic and vagal dysfunction, sympathetic over-excitement, parasympathetic inhibition, so the heart will panic. 5. Hypoglycemia: diabetic patients taking hypoglycemic drugs or subcutaneous injection of insulin dose is too large, resulting in nighttime hypoglycemic episodes, sympathetic nerve excitation and panic. Waking up in the middle of the night with a panic attack may be related to a variety of factors, it is recommended to consult a doctor for a clear diagnosis and treatment according to medical advice.