Lichen planus refers to florid furuncle, which is similar to the clinical manifestations of vitiligo, but it is a different disease from vitiligo and will not deteriorate into vitiligo. Floral furuncle is a fungal infectious dermatosis, caused by Malassezia, which can be manifested as pale white round or oval spots with indistinct borders and fine scales on the surface. Vitiligo onset without the involvement of fungi, mainly for patches of skin pigmentation loss Li was white, its edge may have pigmentation, generally no flaking. The florid chaffing is prone to recurrence, after the discovery of the treatment should be timely, in order to seek a complete cure. Vitiligo should also be treated early after discovery to control the condition and prevent the spread of white spots. To sum up, the patients of florid furuncle and vitiligo need to actively cooperate with the doctor to carry on the standard treatment, regular follow-up, and stabilize the condition.