Abdominal aortic aneurysms are often referred to as “untimely bombs” in the human body, and their rupture often leads to hemorrhage and death. The famous physicist Albert Einstein, Wu Youxun, and geologist Li Siguang all passed away due to aneurysm rupture. Foreign literature reports that the overall mortality rate of aortic aneurysm is as high as 70%-77%, once the aneurysm ruptures, the survival rate is only 50% after 24 hours, 30% after 6 days, and only 10% after 6 weeks, which shows the danger of the condition. Now, this “untimely bomb” appears more often in the body of patients with atherosclerosis and hypertension, how to effectively prevent, timely treatment, remove the “bomb” has attracted the attention of experts in vascular disease. In December 1947, Einstein was accidentally found to have an abdominal aortic aneurysm during surgery for a gastric ulcer, and at that time the medical level in 1947 could not cure the abdominal aortic aneurysm. He was admitted to Princeton Hospital, where doctors diagnosed him with “ruptured abdominal aortic aneurysm” and pointed out that the only way to save him was to operate. After his death, an autopsy of his abdomen by a specialist revealed a large blood clot in his retroperitoneum, which was confirmed to be a ruptured abdominal aortic aneurysm. On November 29, 1977, Mr. Wu Youxun, a famous Chinese physicist, felt unwell, and at eight o’clock the next morning, Wu Youxun suddenly felt a stabbing pain at the root of his thigh, followed by panic, dizziness, dizziness, and instantly turned pale, unable to speak a word. She found that her father’s pulse was gradually weakening, and not long after, the pupils began to spread, and Wu Xiru had sensed that this was a symptom of acute hemorrhage in the body. As a doctor, Wu Xiru, although not a vascular surgeon but a pediatrician, had also initially concluded that the arterial vascular rupture in the thigh near the abdomen had caused blood to gush into the abdominal cavity, and it was too late to save him anyway. When the ambulance arrived the only thing the doctors could do was to try to make a final diagnosis: ruptured abdominal aortic aneurysm haemorrhage. Coincidentally, Wu Youxun’s old friend, the famous geologist Li Siguang, had the same disease and had also died in 1971 from a ruptured abdominal aortic aneurysm. Mr. Wu Youxun’s death took less than three hours from the time he had visible symptoms to 10:50 a.m. Abdominal aortic aneurysms are found deep in the abdomen and are not easily detected at an early stage because of the lack of obvious discomfort. So, how does the human body get this disease? What exactly are the early signs of abdominal aortic aneurysm? Can it be detected early? Is it treated early? We often compare the main roads of transportation, such as highways, to arteries because they play a major role in transportation. The human aorta is the thickest blood vessel in our body, which emanates from the heart and goes to the pelvic cavity, during which it then emanates many branches to supply the brain, internal organs, limbs and other organs. Abdominal aortic aneurysm is not a tumor, but a balloon-like aneurysmal mass caused by the loss of elasticity of the vessel wall due to atherosclerosis of the abdominal aorta, which is formed by the expansion of the artery. However, this mass is filled not with gas but with flowing blood. Due to the continuous impact of blood flow, the mass will rupture when it expands and deforms to the limit (usually more than 5 cm in diameter). The timing of rupture is often sudden and catastrophic and difficult to assess accurately, so it is called an “untimely bomb” in the human abdominal cavity. Most abdominal aortic aneurysms are initially noticed as a pulsating mass in the abdomen, followed by dull pain around the umbilicus or in the upper abdomen, or just abdominal discomfort. When the aneurysm invades the lumbar spine, there may be lumbosacral pain. Sometimes the aneurysm increases in size and may even penetrate into the duodenum or jejunum, thus producing a manifestation of gastrointestinal bleeding. In addition, the enlarged aneurysm may produce some compression symptoms, such as jaundice due to compression of the common bile duct; intestinal obstruction due to compression of the duodenum; renal colic or hematuria due to compression of the ureter; frequent urination and fluctuating urine flow may occur when the bladder is compressed. Sclerotic plaque debris or attached thrombus dislodged within the aneurysm can cause lower extremity arterial embolism and acute or chronic ischemic symptoms in the lower extremities. Early detection of abdominal aortic aneurysm can be achieved with an ultrasound examination, but the general physical examination does not include ultrasound examination of the abdominal aorta. The prevalence of abdominal aortic aneurysms ranges from 63% to 79% of aortic aneurysms, and some patients can be asymptomatic or have symptoms that go unnoticed until rupture or near-rupture occurs. Given the insidious nature of aortic aneurysms, middle-aged and elderly patients with hypertension, coronary heart disease, and cerebrovascular disease should have regular annual vascular surgery visits for ultrasound examination of the abdominal aorta. Einstein lived at a time when the technology for treating abdominal aortic aneurysms was still very immature. In the 1970s, there was not a single hospital in China with a vascular surgery specialty or a full-time vascular surgeon, but now there are physicians in medium-sized cities who carry out vascular surgery. The traditional surgical method for treating abdominal aortic aneurysm is to remove the aneurysm openly and then artificially transplant the blood vessel, this technique requires opening the abdomen, there is a large incision in the abdomen, the surgery is more traumatic, some elderly and frail people cannot tolerate it, some patients can not afford the surgery and postoperative complications and die, some patients are afraid of the trauma and risks associated with major surgery and do not want to operate. From the pathological changes of abdominal aortic aneurysm, we can know that abdominal aortic aneurysm is an expansion of the abdominal aorta rather than a tumor, so as long as we can prevent the rupture of abdominal aortic aneurysm, we can achieve the purpose of curing abdominal aortic aneurysm without removing it. Instead of making a large abdominal incision, a femoral artery puncture or small incision can be made at the root of the patient’s thigh, and an endoprosthesis wrapped with artificial blood vessels is sent upward through the femoral artery to the proximal end of the abdominal aortic aneurysm through a delivery catheter. In this way, the blood flow of the abdominal aorta is maintained and the rupture of the abdominal aortic aneurysm is prevented, which means that the abdominal aortic aneurysm is completely cured. This technique is called “endoluminal isolation”, and the endoluminal isolation of abdominal aortic aneurysms is the product of a combination of intellectual advances and numerous technical developments. Compared to traditional open mega-invasive surgery, endoluminal isolation avoids general anesthesia, open abdomen, and blockage of the aorta, resulting in much less invasive surgery, much shorter operative time, and no blood transfusion for most patients. Patients recover quickly after surgery and can eat on the night of surgery and get out of bed on the next day. The complication rate and mortality rate are also significantly reduced, which improves the safety of treatment and gives many patients who cannot tolerate traditional surgery due to their advanced age and coexisting diseases a chance to be cured. For patients at high risk of aneurysm, especially those with atherosclerosis (smoking, diabetes, high blood cholesterol, and obesity are all risk factors for atherosclerosis) and hypertension, in addition to taking regular antihypertensive and lipid-lowering drugs to keep blood pressure and lipids at normal levels, they should have regular checkups at hospitals to proactively prevent and detect aortic aneurysms. We also call on medical examination institutions not to neglect the examination of the aorta and should include abdominal aortic ultrasound examination as a routine item in the medical examination of middle-aged and elderly people. With proper understanding and early treatment, the “untimely bomb” of abdominal aortic aneurysm can be removed from the body in time.