1. Early pregnancy examination 1. Medical history: name, age, occupation, age at marriage, place of origin, address, height. Menstrual history, history of previous pregnancy and delivery, history of previous diseases, family history. History of exposure to toxic and radioactive substances, history of drug application, history of vaginal bleeding, fluid flow, abdominal pain. 2. serum HCG, E2 and P tests: these 3 tests are usually performed every other week between 4 and 6 weeks of pregnancy; 3. serum thyroid function: HCG during pregnancy can cause a decrease in thyroid hormone, an increase in thyroid binding globulin, a decrease in albumin and an increase in total serum thyroid hormone. Therefore, moderate hyperthyroidism in early pregnancy does not require treatment. However, if hyperthyroidism is severe or hypothyroidism requires medication; 4. serum liver and kidney function, fasting glucose, blood lipids, routine blood count; 5. serum TORCH; 6. ABO/Rh blood group antibodies: if the mother has O blood type and the husband has non-O blood type; or if one of the mother or father has Rh(D)(-), this test is recommended at 10-12 weeks of pregnancy; 7. gynecologic ultrasound Examination: 4-5 weeks of gestation to check for possible ectopic pregnancy. In the 6th-7th weeks of pregnancy, we can find out whether the embryo has germ development and heartbeat; in the 11th-13th+6th weeks of pregnancy, we can find out the embryo development and NT value. In addition, if the patient has a previous history of adverse pregnancy, additional tests such as blood viscosity, serum humoral immunity, serum closed antibody test, serum anti-endometrial antibody and antiphospholipid antibody can be done. Second, mid- and late-term pregnancy checkups After the prenatal checkups and card construction at the community doctor at 12 weeks, if there is no abnormality, prenatal checkups should be done once every 4 weeks from 20 to 36 weeks of gestation, and once a week from 36 weeks of gestation, for a total of 9 prenatal checkups. All high-risk pregnant women should increase the number of prenatal checkups as appropriate. 1.Inquire medical history: find out whether there is dizziness, headache, ophthalmia, edema, vaginal bleeding, fluid flow, abnormal vaginal discharge, fetal movement, etc.; 2.Physical examination: check blood pressure, pulse, weight, uterine height, abdominal circumference; four-step palpation to understand fetal size, fetal previa, fetal orientation, etc.; bony birth canal and soft birth canal examination; 3.Down’s syndrome screening: check at 15-20+6 weeks of pregnancy. If there is a higher risk, amniocentesis and fetal chromosome examination can be performed at 17-21 weeks; 4. Fetal 3D/4D ultrasound examination: 18-24 weeks; 5. Fetal electronic monitoring.