If the ambient temperature is not low, it is most often considered to be vesicular tinea pedis, which is mainly caused by fungal infections such as Trichophyton rubrum or Trichophyton spp. and requires antifungal treatment. If it is in winter and the temperature is very low, you also need to consider the possibility of frostbite. More severe frostbite can cause ulcers and vesicles on the feet with significant itching, and you need to pay attention to keeping warm: I. Vesicular tinea pedis: 1. Medication: Western medicine treats tinea pedis mainly with oral medication and local topical application, immersion, or a combination of oral and topical medication. Topical antifungals have fewer adverse reactions and are less likely to affect liver and kidney function, making them ideal for the treatment of tinea pedis. At present, the commonly used drugs in clinical practice include azole antifungal drugs, one type of imidazole such as miconazole and ketoconazole, another type of triazole antifungal drugs such as fluconazole, terconazole, and itraconazole, and the more commonly used arylamine antifungal drugs are butenafine hydrochloride cream and terbinafine cream. In addition, Chinese medicine fumigation, soaking also has a good effect, if the foot has ulcerated surface, more exudation, available boric acid solution local wet compress; 2, other treatment: such as acupuncture point injection, moxibustion treatment, etc., moxibustion can warm the meridians and promote local blood circulation. Comprehensive treatment mainly includes the combination of Chinese and Western medicines, Chinese herbal infusion with moxibustion or acupuncture, Chinese herbal medicine with physical therapy, etc., which helps to improve the efficacy and the quality of life of patients. Second, frostbite: 1, medication: mainly including anti-inflammatory drugs, such as antibiotic ointment, and vasodilator drugs such as nifedipine, which can shorten the time for frostbite to subside and reduce the possibility of new frostbite, and herbal treatment can be applied to Yanghe Tang, Gui Zhi Hong Hua Tang, Safflower Tang and other formulas; 2, other treatments: such as ultraviolet radiation, audio electrotherapy, helium-neon laser local irradiation, acupuncture, massage therapy, etc., all have certain The treatment is effective. Third, eczema: vesicles with itching symptoms can also be seen in the acute and subacute phases of eczema. Acute lesions can be manifested as erythema, edema, blisters, vesicles, often accompanied by intense itching; subacute vesicles can gradually crust, flaking, itching can be reduced. Oral treatment with antihistamines and topical application of hormonal creams are used.