The incidence of multiple sclerosis differs between men and women, with different ages and geographic regions. The details are as follows: 1. Gender factor: In terms of incidence rate of men and women, the incidence rate of women is higher than that of men. However, different statistics show that the ratio of male to female can range from 1:1.2 to 1:10, with different data at different stages; 2. Age factor: the disease has less incidence before the age of 10 and after the age of 5, with young people having the majority of incidence; 3. Geographical factor: the incidence of multiple sclerosis is also related to geographical location, and the incidence of multiple sclerosis is not the same in different regions. The incidence rate is higher in areas with higher latitude, and generally in these places the incidence rate is more than 3/100,000, or even reaches 1/10000 or a few parts per million; in low incidence areas, the incidence rate is only 1/150,000, or even lower; and the higher the relative latitude the higher the incidence rate, most people move from cold places to high incidence areas from childhood, and some studies have found that the The incidence of multiple sclerosis is reduced. After the age of 14, the incidence of MS no longer changes when people move from colder to lower latitudes. Therefore, the incidence of multiple sclerosis needs to be further observed.