Drugs to control blood uric acid are divided into drugs that inhibit uric acid production and drugs that promote uric acid elimination.
Uric acid is the end product of purine metabolism, the control of blood uric acid can be used to inhibit the production of uric acid and promote uric acid discharge drugs.
1. Inhibit uric acid production of drugs: the more commonly used drugs are febuxostat, allopurinol, the use of febuxostat adverse reactions include nausea, rash, liver function impairment, etc., allopurinol can appear rash, drug fever, liver enzyme elevation and other adverse reactions. Adverse drug reactions need to be closely monitored during the use of the drug.
2. Promote uric acid excretion of drugs: commonly used benzbromarone, probenecid, benzbromarone for glomerular filtration rate <20ml/(min-1.73m^2) or uric acid kidney stone patients are prohibited, the adverse reactions of the drug are gastrointestinal discomfort, diarrhea, skin rash. Probenecid is contraindicated in those who are allergic to sulfonamide.
Patients with increased uric acid are advised to go to the rheumatology and immunology department of the regular hospital in time, and follow the doctor's instructions to standardize the diagnosis and treatment. The medication should be used in accordance with the doctor's instructions, do not self-medicate.