Macroscopy is a 4-dimensional dynamic color ultrasound screening for fetal malformations and is usually best performed around 20-24 weeks of gestation. Grand Rounds can show the face of the fetus in three dimensions, the development of each organ, and the activity of the fetus in the mother’s body. It can diagnose fetal anomalies such as cleft lip, cleft palate, abnormal bone development and cardiovascular anomalies at an earlier stage. If the gestational week is too small, the fetal organs are not mature, and if the gestational week is too large, the fetal body has too much fat deposits, which will affect the results of 4D ultrasound. There are a lot of items done in the Grand Rounds, but it does not mean that if the Grand Rounds is passed, the child will definitely be fine. It is generally recommended to have another ultrasound examination at 28-30 weeks of pregnancy. There is no need to fast and hold urine for the teratology examination. Half an hour before the teratology ultrasound, pregnant women can eat something, drink some water and exercise appropriately to increase fetal movement. During the examination, you should relax properly and relieve tension to avoid interfering with the examination results.