Hypothyroidism and its comorbidities

Hypothyroidism (hereinafter referred to as hypothyroidism) and its comorbidities are increasing year by year. In adults, the disease is often atypical, and is often characterized by a single symptom. It can be a serious consequence of long-term hypothyroidism, and sometimes it can be the first symptom of hypothyroidism, which can be easily misdiagnosed as other diseases. The author applies western medicine to recognize the disease, Chinese medicine to recognize the evidence of a combination of treatment, a little experience. Examples are as follows: 1. Hypothyroidism combined with angina pectoris of coronary heart disease; patient Cen Mou. Male, 63 years old, was admitted to the hospital on November 6, 1986 with the main complaint of 1 day of chest pain in the anterior chest area. Had been in a hospital taking nitroglycerin tablets compound danshen tablets and other symptoms failed to relieve. Body temperature was 36.0℃; pulse was 52 beats per minute; blood pressure was 156/94mmHg; expression was indifferent and unresponsive, hair was thin, skin was rough, and cold limbs were present. The tongue was purple and swollen, and the pulse was sluggish. Heart sounds were muffled, heart boundaries were enlarged, and the liver was two fingers below the ribs. Both lower limbs were swollen and EKG reported low voltage QRS waves with ischemic changes. Chest X-ray reported a significantly enlarged heart with a cardiothoracic ratio greater than 0.60 and a small amount of pericardial effusion. After inquiring about the medical history, it was known that he underwent 131I irradiation 3 years ago due to hyperthyroidism 20 years ago, and his blood tests showed T30.48nmol/L; T425.74nmol/L; TSH5.1mmol/L; TG2.59mmol/L; CH11.89mmol/L. His western diagnosis was hypothyroidism heart disease, angina pectoris, pericardial effusion, and grade II hypertension. Traditional Chinese medicine diagnosis was chest yang weakening, qi stagnation and blood stasis. The treatment is to warm the yang and benefit the qi, activate the blood and remove the blood stasis, the medicine selected jilin ginseng chuanxiong ligustici gui zhi xianmao 10 grams each, astragalus poria zejia 30 grams each, psyllium senna spleen atractylodes alba red peony 15 grams each, baked licorice 6 grams, 1 dose per day, decocted with water for warm service. And with 10 glucose water 500 ml add compound danshen injection 16 ml intravenous drip. 3 days later, chest pain disappeared, symptoms improved, blood pressure 150/82 mmHg, pulse 62 times / min. Above to go to the white atractylodes red peony, add calamus Yu Jin 10 grams each, and then into the 4 doses, chest tightness is also removed, cold and fear of cold improved. The chest tightness was also removed, and the coldness and coldness improved. Add Gui Hui Lizhong Pill 3 times a day, 1 pill each time, and thyroxine tablet 20mg once a day. After months of treatment, EKG improved significantly, pericardial effusion disappeared, T31.85nmol/L, T477.2nmol/L, TSH decreased to 1.53mmol/L, TG1.24mmol/L, CH5.69mmol/L. She was discharged from the hospital with medication on December 30th, 1986.2.Press; this patient was over the age of one year old, due to the irradiation of the thyroid gland with 131I. Thyroid damage and hypothyroidism. The manifestation of heart enlargement, ischemia and hypoxia, resulting in angina pectoris. Now the clinic found that the elderly hypothyroidism combined with coronary heart disease angina pectoris onset quite a lot. Clinical treatment is very tricky. Because thyroid hormone replacement will aggravate angina, and even induce myocardial infarction. At this time, anti-angina drugs may be ineffective, traditional Chinese medicine identification for heart and kidney Yang failure, Qi deficiency and blood stasis, medicinal use of Jilin Shen Guizhi, Astragalus, Xian Ling spleen qi and Yang, Rhizoma Ligustici Chuanxiong Red Peony blood stasis, Poria Poriae Radix Phellodendron Strong cardiopharmacia diuretic, Atractylodes Macrocephala Ze Xie Diarrhea spleen diuresis, hot licorice warming and restoration of the pulse, the combination of all the medicines to enhance the function of the heart, to correct the ischemia and ischemia of myocardial oxygen. Avoided the generation of hypothyroidism crisis. It laid a good foundation for thyroid hormone replacement therapy. Maintained thyroid function and improved the patient’s quality of life.2. Hypothyroidism combined with neuropathy Patient Li, female, 46 years old. Female, 46 years old, laborer. Due to repeated back stiffness, segmental numbness of both upper limbs. Tearing-like pain and abnormal sensation for 3 years. On December 16, 1992, she came to the clinic. She was diagnosed as spinal cord cavernous disease in a hospital, and was treated with energy and neurotrophic agents, but her symptoms did not improve. She had constipation, drowsiness, poor appetite and slow movement. She was found to have swelling of both lower limbs, rough skin, pale tongue with teeth marks, slow pulse, heart rate of 50 beats per minute, blood test, T30.924nmol/L; T42.16nmol/L; TMG40/L. TMA35. Traditional Chinese medicine diagnosis was spleen and kidney yang deficiency. The treatment was from strengthening the spleen and tonifying the kidney, warming the yang and benefiting the qi. The medicine selected Angelica sinensis, Rhizoma Ligustici Chuanxiong, Rhizoma Ligustici Duhuo, Gui Zhi, Rhizoma Atractylodis Macrocephalae, Qin Jiu, Wei Ling Xian, Di Long, 10 grams of each, Astragalus, Job’s tears, Sang Mang Sheng, 30 grams of each, licorice 3 grams. Thyroxine tablets 20mgbid inosine tablets 0.4tid viloxan 2 tablets tid with the treatment. 10 days later, the pain in both upper limbs was significantly reduced, and the spirit improved. Continuing the above prescription increase and decrease antler cream Gan Song, turtle plate dog ridge knee papaya and other drugs, 2 months later, numbness and pain in the limbs disappeared, the skin is fine and moist with zephyr, normal sensation, double lower limb swelling disappeared. Blood test T31.6nmol / L; T472.07nmol / L. To be thyroxine tablets 20mg qd, inosine tablets 0.4tid viloxan 2 tablets tid maintenance, traditional Chinese medicine to tiger submerged pills to go to ZhiMu, HuangBai, add GuiZhiDiLongHuangAstragalus, Deer horns cream and so on good after, so far normal. By the way; there are many cases of hypothyroidism combined with neuropathy. However, there are not many manifestations similar to spinal cord cavernosis. Back stiffness, limb numbness and pain, sensory abnormalities are caused by hypothyroidism, and this case of hypothyroidism may be caused by the sequelae of Hashimoto’s thyroiditis. Neurotrophic agents alone were ineffective. After clear diagnosis, seize the main contradiction, to be thyroid hormone to improve thyroid function, with traditional Chinese medicine to warm Yang and activate blood, strengthen the spleen and qi, tonifying the kidneys and collaterals, so that Yang qi can be restored, swelling can be eliminated, numbness and pain disappeared, and all the symptoms are healed. 3. Hypothyroidism with stasis bile hepatic damage. Patient Deng Mou, female 48 years old, farmers, to abdominal distension and constipation, anorexia belching, shin swelling limb weakness, fear of cold and fatigue for six months, dizziness amenorrhea 3 months, diagnosed as menopausal syndrome in a hospital, and ethylphenol treatment is ineffective. ultrasound report; liver and gallbladder moderately enlarged, but no stone. Liver function report; jaundice index 16ui, serum bilirubin 37.62umol/L; ALT1334mmol/L; rGT140UI; HBESAg negative; TG3.2mmol/L.ch10.3mmol/L. She used to take liver tylenol, hepatolynine ranitidine, morbidin, and other symptoms did not improve. On March 3, 1994, she came to TCM for treatment. History, 3 years ago there was high fever, goiter. It was cured by treatment. She then found T30.63nmol/LT42.57nmol/L. Western medicine diagnosed hypothyroidism with stasis bile liver damage. The TCM diagnosis was yin-yellow. The treatment was to warm yang and strengthen the spleen, and to promote dampness and remove yellowness. Astragalus 30 grams, Salvia miltiorrhiza, Poria, Poria, Psyllium 15 grams, Acorus calamus, Uljin, Citrus aurantium, Gui Zhi, Atractylodes macrocephala 10 grams, licorice 3 grams, 1 dose per day. And give thyroxine tablets 20mg once a day, vitamin B120mg 3 times a day. 10 days later, jaundice subsided significantly, food improved, stool normal. After another 10 days, the abdominal distension was removed and the swelling of the shin was eliminated. After 2 months of treatment, the symptoms were eliminated, menstruation came, and the liver function report was normal. According to modern medicine, hyperthyroidism is characterized by hypermetabolism, decomposition of hepatic glycogen, consumption of amino acids and vitamins, which may easily lead to liver enlargement and hepatic function damage. Clinically, hepatocellular jaundice and increased ALT are not uncommon side effects of antithyroid drugs. Combined with the history, clinical manifestations, and treatment results, this case can be identified as subacute thyroiditis with hypothyroidism, causing stasis bile liver damage. She had amenorrhea, abdominal distension, anorexia and lethargy. Therefore, estrogen and hepatoprotective drugs were ineffective. Chinese medicine is recognized as yin-yellow, and the treatment is to warm the yang and benefit the qi, strengthen the spleen and benefit the dampness, and cooperate with thyroxine to improve the thyroid function, so the effect is remarkable. Note: This article was published in Fujian Journal of Traditional Chinese Medicine, October 1999, Issue 5, page 22.