Treatment of premature ejaculation includes psychological and behavioral therapy, local treatment, oral medication and surgery. The goal of treatment is to improve the patient’s ability to control ejaculation by increasing the sensory domain values of the penis and adjusting behavioral reflexes. Psychological and behavioral treatment for premature ejaculation requires a professional psychiatrist and the effectiveness is closely related to the experience of the doctor. The purpose of local penile treatment is to reduce the sensitivity of the penile head and penile skin and increase their sensory domain values. Topical treatment commonly uses 2% lidocaine gel, applied to the head of the penis 10 minutes before intercourse, to reduce the sensation of the penis and prolong the latency of ejaculation. It can be washed off or with a condom during sexual intercourse. The shortcomings of topical treatments for premature ejaculation are numbness of the penile head and decreased pleasure. There are no drugs specifically for premature ejaculation. Doctors at home and abroad commonly use drugs for depression such as tricyclic antidepressants (chlorpromazine, etc.) and selective 5-hydroxytryptamine reuptake inhibitors (fluoxetine, sertraline and paroxetine, etc.) to treat premature ejaculation. These medications are slow to take effect and usually require two weeks of continuous medication before the ejaculation time is felt to be prolonged. Once the medication takes effect, it can also be taken as needed 3-4 hours before sexual intercourse. The adverse effects of these drugs are nausea, dizziness and erectile dysfunction. Surgical methods for premature ejaculation are less commonly used. The main principle is to selectively cut the sensory nerves in the head of the penis to reduce the sensitivity of the head. These are just the basics of premature ejaculation, and those with problems need to go to the hospital.