There is no definite answer to the question of how long a toothache can last on ibuprofen. It depends on the degree of pain, the cause of pain, and the dosage of ibuprofen chosen by the patient. If the toothache is clinically severe, such as acute pericoronitis of wisdom teeth, acute pulpitis, acute apical inflammation, the effect of ibuprofen is also very high. The effect of taking ibuprofen is also limited. It can only slightly relieve the pain, but generally does not provide complete pain relief. For these cases, the best way is to recommend patients to go to a professional dentistry department for symptomatic treatment as soon as possible. There are many different clinical forms of ibuprofen, including ibuprofen suspension for children. Its duration of action is usually 4 to 6 hours. The duration of action of ibuprofen may be up to 12 h. Therefore, the duration of action of ibuprofen may vary depending on the formulation. The specific duration of action can only be seen after the patient has taken it. However, it is advisable to consult a professional physician or pharmacist before using the medicine.