Pediatric rotavirus generally has a duration of illness of 5-7 days. There are no effective anti-infective drugs available to treat pediatric rotavirus, except for vaccination to reduce infection. The clearance of pediatric rotavirus relies on the child’s own resistance to clearance, and the production of autoantibodies usually takes about a week. However, due to individual differences, the time to produce antibodies may fluctuate by 2-3 days, so the duration of the disease is usually around 5-7 days. After rotavirus infection in children, diarrhea usually occurs, with more than 10 stools per day, mainly in the form of egg-flake soup-like stools. A routine stool examination may indicate rotavirus infection. Therefore, if a child is diagnosed with rotavirus infection and has excessive diarrhea, the key therapeutic measure is timely rehydration to avoid dehydration and water and electrolyte disorders in the child. The child’s family should be kept hydrated to prevent dehydration, and in severe cases, intravenous saline rehydration should be administered promptly. After rotavirus infection, we should consider the possibility of taking drugs such as montelukast and tetracycline to stop the diarrhea according to the doctor’s prescription. If the child has fever and other symptoms, you can consult your doctor before feeding fever-reducing drugs, and you can also take warm baths and other physical cooling methods.