In the clinic, we often encounter patients with labs and a worried face asking, “Doctor, I’m a major triple-positive patient, my condition must be very serious, right? How can I change to a minor triple-positive?” In fact, the severity of the disease is not judged by whether it is “major tri-positive” or “minor tri-positive”, but by the condition of the patient’s liver function. Regardless of whether it is “major triplet” or “minor triplet”, as long as the liver function is normal (including transaminases, bilirubin, albumin, etc.), it indicates that there is no obvious hepatitis activity and the condition is basically stable. On the contrary, if the liver function is abnormal, with elevated transaminases and even bilirubin, it indicates hepatitis activity or even liver cell necrosis, which should be treated actively. It is also important to know that there is no single group of patients with “major triple yang” or “minor triple yang”, as patients with “major triple yang” include asymptomatic carriers in the immune tolerance phase and those in the immune activation phase. The “major triple-positive” patients include asymptomatic carriers in the immune tolerance phase and chronic hepatitis patients in the immune activation phase, while the “minor triple-positive” patients include HBeAg-negative chronic hepatitis B patients and inactive HBsAg carriers in the inactive phase. Therefore, when you go to the hospital for a checkup, in addition to the five hepatitis B tests, you also need to check your liver function so that your doctor can make an accurate judgment of your condition. If you are a patient with “major triple-positive” and your liver function is normal, then you are in the immune tolerance stage and you do not need treatment at this stage, as long as your liver function is checked regularly.