Mycoplasma infections can cause serious damage to the urinary system, producing acute cystitis and acute urethritis, usually with clinical manifestations such as fever, abdominal pain, urgency, frequency and painful urination. Routine urine tests show leakage of red blood cells, white blood cells, and protein, so mycoplasma infection urine routines can be abnormal. The treatment can use macrolide antibiotics, such as roxithromycin, azithromycin for treatment, and also quinolone antibiotics, such as ciprofloxacin, levofloxacin and other symptomatic treatment. It is recommended to drink more water to reduce the possibility of re-infection of the urinary system.