Pharmacologic liver injury refers to liver injury induced by taking all kinds of prescription or over-the-counter medicines, biological agents, Chinese medicines, natural medicines, health products, dietary supplements and their metabolites and even excipients. The main symptoms include fever, fatigue, jaundice, skin itching, and ascites in severe cases.
1. Acute drug-induced liver injury: mild cases may have no obvious symptoms, while severe cases may have digestive symptoms such as fever, jaundice, itchy skin, fatigue, loss of appetite, anorexia, pain in liver area and so on.
2. Chronic drug liver injury: refers to the duration of drug liver injury is more than 6 months, in addition to the acute stage performance, patients due to the prolonged course of the disease may also appear cirrhosis portal hypertension symptoms, such as hepatomegaly, ascites, gastrointestinal bleeding and so on.
When drug-related liver injury occurs, first of all, the drug that causes liver injury must be stopped, and can be treated with drugs such as reduced glutathione and ursodeoxycholic acid, and should seek medical treatment in time to avoid delaying the condition.