The term “hepatitis B” is commonly used to refer to a blood test that shows a positive marker for hepatitis B. A blood test may also show a positive result for HBeAg and anti-HBe. If HBsAg, HBeAg, and anti-HBe are positive at the same time, which is what we usually call 1, 3, or 5 positive, that is, the “major triplet”, which is usually more infectious, but to clarify the strength of the infectiousness, HBV DNA quantification is required. DNA refers to the amount of HBV in the blood, the higher the quantitative value of HBV DNA, the more infectious, and vice versa, the less infectious. If HBsAg, anti-HBe and anti-HBc are positive at the same time, that is, we usually say 1, 4, 5 positive, that is, “small three yang”, most “small three yang” patients with low HBV DNA quantitative value, usually less than 500 copies/ml However, a small number of people have HBV DNA quantification values greater than 500 copies/ml, and like “major triplets”, the higher the quantification value, the stronger the infection. If the pre-pregnancy examination reveals that the person is positive for hepatitis B and HBV DNA is <106 copies/ml, and the liver function is normal, this group of people can get pregnant normally. If there is no change, no special treatment is needed during pregnancy. If the pre-pregnancy examination reveals that the hepatitis B is positive and the HBV DNA is >107 copies/ml, and the liver function is normal, this group of people can also have a normal pregnancy, closely monitor the liver function after pregnancy, and recheck the hepatitis B two-to-one half and HBV DNA in the middle pregnancy. The success rate of infant interruption will be significantly increased if hepatitis B immunoglobulin and hepatitis B vaccine are administered in a timely manner after delivery. If pre-pregnancy tests show abnormal liver function, jaundice or elevated transaminases, you must ask your doctor to make an accurate assessment of your condition before preparing for pregnancy. The application of antiviral drugs is generally not recommended before or during early pregnancy. After pregnancy, regular check-ups at a specialist hospital are necessary to have close monitoring by a doctor to keep track of changes in liver function and apply liver-protective drugs or add antivirals in a timely manner if necessary. For patients with more severe or complicated hepatitis such as cirrhosis decompensated, antiviral therapy or drug resistance, a consultation and discussion between obstetricians and gynecologists and hepatologists is needed to make an individualized plan according to each patient’s condition.