Sore throat may be caused by cold, acute pharyngitis, laryngitis, tonsillitis, retropharyngeal abscess or laryngeal cancer, etc., which can be treated with medicine or surgery. 1. Common cold: pay attention to rest, drink more water, light diet, etc. For the treatment of viral infection, we can use ribavirin, acyclovir, etc., and when the swelling and pain in the throat is obvious, we can use ibuprofen and diclofenac sodium for symptomatic treatment. 2. Acute pharyngitis: local can use compound borax solution gargle, with systemic symptoms to clarify the causative organisms and choose the appropriate antibiotics for anti-infection treatment, such as amoxicillin, cefaclor and so on. 3. Acute laryngitis: oral broad-spectrum antibiotics or budesonide suspension nebulized inhalation treatment. Pediatric acute laryngitis onset of acute, once diagnosed, should immediately take measures to lift the obstruction, to ensure that the airway is open. 4. Acute tonsillitis: generally viral will be self-healing, bacterial need antibiotic treatment such as penicillin. 5. Retropharyngeal abscess: exclude tuberculosis, incise and drain pus, if tuberculous, carry out systemic anti-tuberculosis treatment, inject streptomycin through intraoral puncture. 6. Laryngeal cancer: the main treatment methods include surgery, radiotherapy and chemotherapy. When sore throat occurs, it is necessary to consult doctor in time, after clarifying the cause and degree of illness, use standard medicine or surgery under doctor’s guidance.