During pregnancy, the blood is in a hypercoagulable state, and D-dimer reflects the body’s coagulation function. The concentration of D-dimer in the body also varies with the week of pregnancy, gestational age and the number of pregnancies. If the test data is slightly higher compared to the reference value, i.e., if the D-dimer is slightly elevated, in most cases it is considered to be related to the hypercoagulable state of the body during pregnancy. If this indicator is significantly elevated, it suggests the possibility of a blood clot or the presence of a malignant tumor. If it is slightly elevated, it can be regulated under the guidance of a doctor, with reasonable and correct use of anticoagulant drugs and regular follow-up and close observation. Pay attention to the adjustment of diet, try not to eat fried food, and do not eat kimchi, pickles and other high-salt food. It can be improved by eating more foods rich in dietary fiber and performing appropriate activities every day. If it is significantly elevated, it indicates that there may be thrombosis in the body, or it may be caused by malignant tumor, trauma, etc., and it needs to be examined to check for other diseases. In addition, it should be noted that the reagents and methods for testing D-dimer may vary from hospital to hospital, and the reference range may also be different, so the diagnosis should be made according to the criteria of the hospital’s laboratory test.