The acute phase can present with high fever, chills, nausea and vomiting, yellow sclera, and abdominal pain that can radiate to the right shoulder and worsen in paroxysms.
The chronic phase can be asymptomatic or mild; the moderate phase may lack appetite, indigestion, diarrhoea, may have hepatomegaly, pressure and percussion pain, but also weakness, anaemia, oedema and other systemic symptoms; and the severe phase has further aggravation of symptoms, gastrointestinal symptoms are more obvious; liver damage is serious, such as a large number of adult worms blocking the bile ducts and obstructive jaundice, can gradually develop into cirrhosis, advanced cirrhosis further causes portal hypertension, splenomegaly, ascites and other conditions, and finally can be complicated by infection, liver coma and other conditions.
In severely ill children, chronic anaemia and malnutrition impede growth and development, leading to dwarfism.