The main treatment for fibroids is First, expectant therapy, mainly for patients with small fibroids and no indications for surgery. For example, a young woman in her 20s with 1-2 cm fibroids does not need special treatment clinically, but just observation and follow-up, including the change of fibroid size, location and whether it is harmful to the woman. Some patients strongly demand medication to inhibit the growth of small fibroids, but there is no medication to inhibit the growth of small fibroids, so expecting treatment is actually no treatment. Second, surgical treatment, most fibroids grow to a certain degree need to consider surgery, surgery is mainly to solve the symptoms caused by fibroids, such as increased menstrual flow, urinary frequency, urinary urgency, bowel pressure and other symptoms, special parts of the cervical part of the fibroids compression of the ureter, etc.. Third, drug treatment, mainly for some special people can choose drug treatment. Firstly, surgical treatment is introduced, and the indications include 1. Uterine fibroids grow faster and cause clinical symptoms, so be alert to whether there is a risk of malignancy. Although the malignancy rate of fibroids is less than 0.5%, the possibility of malignancy cannot be ignored. 2. Clinical symptoms are obvious, such as bladder pressure symptoms are obvious, and patients have symptoms such as frequent urination. Fibroids located in the submucosa, or larger fibroids between the uterine walls can lead to anemia in patients and require surgical treatment. 3. The location of fibroids is not good, causing deformation of the uterine cavity leading to infertility, or the location of fibroids is very close to the fallopian tubes, affecting fertility. 4. Fibroids in special areas such as cervical fibroids, even though they are not very large in size, may compress the ureter, or the fibroids may increase in size making surgery difficult, also requiring early surgical intervention. Open surgery is the basis of all surgeries, and multiple and larger interstitial myomas or bulky subplasmic fibroids can be solved by open surgery. Today, laparoscopic surgery is more often performed for fibroids, which is relatively less invasive and results in faster recovery for the patient. The treatment of fibroids that we are talking about nowadays is mainly total hysterectomy and myomectomy. In principle, if the uterus is particularly large, especially if the uterus is more than 3 months pregnant, laparoscopic surgery should be chosen when it is difficult. Nowadays, many patients who require preservation of the uterus can choose open or laparoscopic surgery for myomectomy. Laparoscopic surgery requires certain surgical skills, which are also fully competent for better laparoscopic techniques. For smaller submucosal fibroids protruding into the uterine cavity, a more minimally invasive approach hysteroscopy can be chosen to operate, and these procedures are well established. In order to reduce side effects clinically, it is essential to improve surgical skills as a surgeon, and it is also important to choose the right surgical approach. For example, uterine fibroids are too large for laparoscopic surgery, and the single-minded pursuit of laparoscopy may prolong the operation, increase bleeding, and fail to achieve minimally invasive results; for patients who have not had children to perform myoma removal under laparoscopy, excessive electrocoagulation, electrodesis, and poor suturing techniques cause a lot of potential risks of uterine rupture. A good selection of surgical indications along with good surgical skills, less intraoperative bleeding, and less trauma is best for the patient. Mifepristone is a progesterone receptor antagonist that mainly inhibits ovulation and allows the patient to achieve amenorrhea. So some patients can be treated with mifepristone for some time before surgery. Mifepristone is mainly used for: Mifepristone is very good for patients who are anemic. Nowadays, blood supply is tight and if the anemia is severe before surgery, blood transfusion is needed before surgery. The drug is used to keep the patient amenorrheic so that the patient’s hemoglobin rises to a level that can tolerate the surgery. The patient will also recover better when the surgery is performed when the patient’s organism is in better condition. Patients with large fibroids can take mifepristone for 3 months in advance for the purpose of reducing the size of the uterus and the fibroids, perhaps with laparoscopy, which previously had to be open, and the patient will have more options. Patients who need a total hysterectomy can avoid the damage of a total hysterectomy by controlling the fibroids with medication and shrinking them.