Intra-anal condyloma acuminatum not treated for 2 years may appear warts increase in size and increase, necrosis, bleeding, infection, cancer and so on. The acromegaly is a kind of sexually transmitted disease that is more difficult to treat and has a higher recurrence rate, especially in some parts, such as the anus because of the local environment, the local moist, so that is more suitable for the growth of the acromegaly virus, the treatment is also more difficult, if you do not treat it, it is more likely to develop, resulting in the increase in the range of the spread of the acromegaly. The first thing you need to do is to get the warts to grow up and become like papillomas, corns, cauliflowers, or even bigger, which can lead to localized occupancy and affect the normal function. At the same time this oversized warts, may be due to the central part of the ischemia and necrosis, bleeding, vesicles, ulcers, secondary infection and so on. If the warts are caused by high-risk HPV infection, there is also a risk of malignancy, or cancer, if left untreated for a long period of time.