Success rate of single sperm injection

  According to foreign statistics, a healthy woman with clear fallopian tubes and normal germ cells has only a 25% chance of conceiving naturally each month, while the chance of getting pregnant through IVF is about 50%, and experts from the Center for Reproductive Medicine point out that choosing a public tertiary hospital can better guarantee the success rate of IVF.  Is the success rate of single sperm injection high?  In the single sperm injection technique, the removed sperm is first processed in the laboratory, washed in vitro and incubated in an incubator for backup. The sperm is then injected into the oocyte plasma using a microsyringe that aspirates the sperm, and the injected egg is transferred to an incubator for incubation until the embryo is transferred into the woman’s uterus. This procedure avoids the free fertilization process of sperm and egg, instead, the selected sperm is directly injected into the selected egg to complete fertilization, which effectively increases the conception rate and is suitable for infertility caused by oligospermia, weakness, deformity and azoospermia.  Factors affecting the success rate of IVF 1. Patient infertility causes: older primary infertility, severe endometriosis with uterine malformation, polycystic ovary syndrome patients from severe oligozoospermia, azoospermia patients who do not get sperm in the testes, or those with a large number of deformed sperm, and those with deformed eggs or abnormal development, etc., also have a higher failure rate in IVF treatment.  2, age: age is an important factor in the success of IVF technology, domestic and foreign literature reported that the age of 25-34 years old the highest success rate, up to 45%, greater than or equal to 35 years old after the success rate of 26%-30%, greater than 35 years old after the success rate will decline, greater than 40 years old success rate of about 20%, and the live birth rate decreased significantly, and the eugenics The success rate of live birth is obviously decreased, and the impact on eugenics is also greater. When over 45 years of age, IVF treatment cannot be performed with one’s own eggs because the success rate is extremely low and the embryos are prone to chromosomal abnormalities. The rate of miscarriage is much higher in the older age groups in IVF treatment, and the rate of premature births and stillbirths is also higher than in younger pregnancies.  3. Chromosomes: In some couples with primary infertility or a history of bad pregnancies, there are some couples with normal variant chromosomes. These couples with chromosomal problems can conceive through IVF technology, but the failure rate and miscarriage rate are higher. Intrauterine environment: The endometrium is the most important site for embryo implantation causing damage to the endometrium, myometriosis, endometritis, endometrial polyps or other lesions of the endometrium may cause the embryo to fail to implant and affect the success rate. New research has found that the endometrium secretes a special sugar molecule, and when this sugar molecule is lacking, the conception rate is greatly reduced. It is believed that in the near future, medical doctors will overcome this problem and improve the success rate of pregnancy.  4. Excellent embryo rate: When there is a problem with sperm and egg, no fertilization or fertilization without oogenesis cannot complete embryo transfer, excellent embryo is an important condition for success. According to the six levels of embryo grading method: fresh embryos of grade I and IV are all available for transfer, and grade I. II are excellent embryos. At present, excellent embryos are only morphologically classified and the potential of embryos is not known. Now, embryologic chilblains are working on a more advanced method of embryo assessment that will hopefully predict the probability of conception of embryo sculptures. However, excellent embryos also require a good uterine environment, good endocrine conditions, and the physician’s superior embryo transfer technique. Couples of normal reproductive age who have intercourse for 1 month according to the time of draining have only about 20% chance of pregnancy. So we hope to have a good attitude during the treatment, which is also an important factor for success.