OBJECTIVE: To investigate the degree of inhibition and destruction, odor improvement, and the quantitative and efficacy relationships of β-ray radiation therapy alone on axillary odorant sweat glands. Methods: 126 patients were irradiated with Siemens PRIMUS linear gas pedal, β-ray, 6-9 MeV, different thickness bioequivalent film, DT18-24 Gy, 300-500 cGy/(f・d) vertical irradiation with a large split, 0.5-1.0 cm outside the outer edge of the axillary hair after skin preparation, and the set dose reference depth: 0.75-1.0-1.5-2.0 cm. DR is about 95% to 100%. The target area DR was about 95%-100%. The radiation treatment was carried out by forming a suitable electron wire lead pattern. Results: 90% (113/126) of the patients showed inhibition of sweat glands and less sweating; 99% (124/126) of the patients showed improvement in odor reduction; 90% (113/126) of the patients showed disappearance of odor; 2% (2/126) of the patients showed no effect. Adverse effects: Grade I acute local skin radiodermatitis was rare (<10%), and 25% (32/126) of patients had mild local skin pigmentation. Conclusion: Simple β-ray radiation therapy for axillary odor is feasible, applicable and effective.