Axillary odor, also known as “fox odor”, is a common genetic skin disease. Common in young adults, especially in women; symptoms vary in severity, and can be reduced or disappear in old age; aggravated in summer when sweating increases. Axillary odor does not affect human health, but in today’s frequent interpersonal interactions can easily bring great psychological pressure and low self-esteem, affecting the patient’s work, study and life. Axillary odor is caused by the decomposition of organic matter in the secretions of the top sweat glands by epidermal bacteria on the surface of the armpit to produce unsaturated fatty acids. The bacterial decomposition of the skin does not explain the genetic characteristics of axillary odor and the characteristics of youth onset, and simple bactericidal treatment does not cure axillary odor. Treatment of axillary odor: 1, drug therapy. Application of antibacterial, astringent, antiperspirant, antiseptic and anti-odor drugs directly coated in the armpit to get rid of odor. Such as 75% ethanol rubbing armpit, 3% tincture of iodine intermittent rubbing armpit. Drug treatment is simple and fast, easy to operate, non-invasive; but this method is only applicable to patients with a lighter degree, and can not be cured, long-term use of drugs will also appear skin complications. 2.Minimally invasive treatment. (1) Injection therapy. Injecting anhydrous alcohol, botulinum toxin, and hot 0.9% sodium chloride solution into the subcutaneous layer of bilateral axillae to necrotize the tissue around the axillae and destroy the sweat glands, or to make the sweat glands atrophy and reduce or eliminate the secretion of sweat glands to achieve the purpose of treatment. The lyophilized powder of botulinum toxin type A, IOU, was injected into the deep layer of axillary dermis with 2.5ml of 0.9% sodium chloride solution diluted to treat 42 cases, and the effective rate was 96.2% in 26 severe cases and 93.8% in 16 mild cases. The above method is simple, less painful and shorter treatment time, but the frequency and dosage of drug injection are not easy to master. The level and location of injection requires high level of doctor. (2) Physical therapy. The use of freezing, laser, ionization, microwave and other methods to produce a local cold effect or thermal effect in the axilla to achieve the purpose of destroying the degree of sweat glands. This method has less bleeding, low chance of infection, less pain and less scarring, but the operator needs to master the use of the instrument, too deep or too shallow can not achieve effective treatment. (3) Surgical treatment. The purpose of surgery is to remove the sweat glands in the subdermis and subcutaneous tissues, which is the most effective and thorough treatment. The most effective and most thorough treatment is to remove the entire skin layer of the axilla, ultra-thin flap formation with a single or double parallel crease incision in the axilla, scraping of the subcutaneous sweat layer of the axilla, and aspiration of the subcutaneous sweat gland of the axilla. (4) Other treatment methods. Thoracic sympathectomy, i.e., using thoracoscopy to cut the T2-T4 nerves that govern the secretion of sweat glands in the palms and axillae. This method does not leave a wound in the axilla, but the thoracoscope damages the chest organs, and postoperative complications such as dry skin on the hands can occur, so it is rarely used in the clinic. With the development of society and the pursuit of higher and higher quality of life, the problem of armpit odor has become more and more prominent. Although there are many ways to treat armpit odor, it should be different from person to person, and you can choose a personalized treatment plan.