The tightness in the chest and wanting to vomit after eating at night is usually caused by indigestion, gastric ulcer, gastroenteritis and other reasons, usually can take general treatment, medication and other methods of treatment. 1. Indigestion: indigestion is usually caused by the patient’s bad dietary habits, there may be stomach acid, bloating and other symptoms, may also be accompanied by chest tightness and vomiting after eating at night, usually need to change the diet to ease, but also can be used to domperidone, mosapride and other medications, drug allergies are prohibited. 2. Gastric ulcer: gastric ulcer patients usually appear after meals, stomach pain, bloating and other symptoms, some patients may be manifested as chest tightness after meals, want to vomit. Omeprazole and other drugs can be used to inhibit the secretion of gastric acid, the use of colloidal bismuth pectin and other mucosal protective agents to protect the gastric mucosa. For the presence of Helicobacter pylori infection, you can also use gentamicin, metronidazole and other drugs. 3. Gastroenteritis: generally caused by bacterial infection of gastroenteritis, may appear abdominal pain, nausea and other symptoms, may also appear after the evening meal chest tightness and want to vomit, generally through the ciprofloxacin, levofloxacin and other drugs for the treatment of drug allergy is prohibited. It is recommended that patients with symptoms of chest tightness and vomiting after eating at night go to the hospital in a timely manner, under the guidance of the doctor to identify the cause of the standardized treatment, do not self-medication.