Rheumatic diseases are common diseases such as rheumatoid arthritis, ankylosing spondylitis, osteoarthritis, etc. The treatment drugs used for each disease are different and cannot be generalized. 1. Rheumatoid arthritis (1) Non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen, are used to reduce joint swelling and pain. (2) Glucocorticoids: such as prednisolone, etc., used to control inflammation. (3) Disease-improving antirheumatic drugs: such as methotrexate, which is used to slow down the progression of the disease. 2. Ankylosing spondylitis (1) Non-steroidal anti-inflammatory drugs: such as celecoxib, etc., used to improve pain, as the first choice of therapeutic drugs. (2) Biological agents: such as tumor necrosis factor antagonists, such as adalimumab, etc., used to inhibit the immune response. 3. Osteoarthritis (1) Non-steroidal anti-inflammatory drugs: such as etoricoxib, etc., used to relieve joint pain. (2) Glucosamine sulfate: used to slow down the degeneration of cartilage. It is recommended that patients with rheumatism go to the rheumatology and immunology departments of regular hospitals and other related departments, follow the doctor’s instructions to standardize the diagnosis and treatment, and do not self-medication.