Hip dysplasia is one of the common causes of hip pain and dysfunction, easily misdiagnosed as aseptic necrosis of the femoral head, early can take anti-inflammatory pain medication management, such as ineffective and affect the activities of the person who often need surgical treatment. In our hospital, from 1995 to 2009, 65 cases of osteoarthritis secondary to hip dysplasia in adults with 71 hips underwent total hip arthroplasty, of which 16 cases of 32 hips were bilateral and 49 cases were unilateral. There were 43 cases of low dislocation, 18 cases of middle dislocation and 4 cases of high dislocation. There were 5 cases of large bone grafting, 13 cases of pellet grafting, and 1 case of acetabular placement in a prosthetic socket. Biological acetabulum 68 hips, including spiral acetabulum 18 hips. Cemented acetabulum 3 hips. RESULTS: At postoperative follow-up of 6 months-13 years, the Harris score increased from a mean of 42.6 points preoperatively to 85.9 points postoperatively. CONCLUSION: Total hip arthroplasty is an effective treatment for osteoarthritis secondary to developmental dysplasia of the hip joint. Intraoperative deepening of the acetabulum and acetabular implant reconstruction according to the degree of acetabular defect is important for improving joint survival. Fu Zhihou, Department of Orthopedic Diseases, Jinan Military General Hospital, Jinan, China