Fat liquefaction is usually seen after surgical trauma, and how long it takes to heal depends on the extent, degree and location of fat liquefaction, the patient’s constitution and the presence of complications, etc., and requires a case-by-case analysis. The time to heal from fat liquefaction is affected by various factors. In general, as long as fat liquefaction is detected in time and adequately drained, it can heal quickly with a good nutritional status of the body and no secondary infection. Specifically, if the fat liquefaction is small and superficial, especially in the extremities, there is less fatty tissue and healing is faster, usually in about 1 week. If the fat liquefaction is more extensive, such as fat liquefaction in the abdomen, it usually takes 2 weeks to heal because there is more fat in the abdomen and it is more extensive and relatively deep. In addition, if the patient develops complications such as infection and bleeding, a second surgery may be required to remove the bleeding or infected foci, and the healing time may be extended accordingly. Patients with fat liquefaction should follow the doctor’s instructions and perform surgical treatment such as wound dressing change in a timely manner. The doctor will check the healing situation during the dressing change and can deal with abnormalities when they are found.