The misuse of antibiotics in the clinical setting is alarming, especially at the county level and below!!! The following 15 categories of causes all lead to elevated routine blood white blood cells, and only bacterial infections in the first category require broad-spectrum antibiotics, viral infections do not require antibiotics, and other infections use highly targeted antibiotics. The other 14 categories are without antibiotics. The causes of elevated blood white blood cells: 1, infection Bacteria, viruses, mycoplasma, chlamydia, fungi, rickettsia, parasites, protozoa, spirochetes. 2.Stress Vomiting, trauma, emotion, environment, temperature. 3.Drugs Glucocorticoids (dexamethasone), leucovorin. 4.Tissue injury Herpes pharyngitis, herpes gingivostomatitis, hand, foot and mouth disease. 5.Hematologic diseases Leukemia. 6.Neoplastic diseases. 7.Allergic diseases Acute urticaria. 8, connective tissue diseases Kawasaki disease, JIA. 9, food factors. 10.Physical factors. 11.Chemical factors. 12.Physiological Newborn baby, pregnant woman, exercise, full meal. 13.After splenectomy. 14.Hemoconcentration In dehydration. 15.Laboratory error.