Premature ejaculation is characterized by the following types of Chinese medicine: damp-heat in the liver meridian (the liver meridian feels damp-heat evil qi), yin-deficiency and fire-exuberance (deficiency of yin and essence in the body, which leads to hyperactivity of deficiency and fire), deficiency in the heart and spleen, and lack of solidity of the kidney qi. In this case, Longdian Diarrhea Liver Tang can be used to treat the symptoms of Damp-Heat in the Liver Meridian. Premature ejaculation with dampness-heat of liver meridian can be manifested as easy to lift the penis, but ejaculation is too early during intercourse, scrotum is swollen and moist and itchy, accompanied by dry throat, bitter taste in the mouth, distension and pain in the chest and ribs, burning sensation at the opening of the urethra when relieving urination, dark yellow urine, red tongue, yellow and greasy moss, and stringy and slippery pulse. The treatment often uses gentian diarrhea liver soup plus subtractions to clear and diarrhea liver meridian dampness and heat. Clinical use of gentian herb, gardenia, chaihu, scutellaria, zejia, wood through, psyllium, raw rhizoma, angelica, cypress, Wu Yao and so on. Among them, gentian herb, scutellaria baicalensis, gardenia can clear liver meridian fire, ze diarrhea, psyllium, wood pass, cypress can clear heat and diuresis (remove the body’s heat and dampness), Wu yao, chai hu can dredge the liver qi, the raw huang, angelica can nourish yin and soften the liver, all the medicines work together to clear and diuresis liver meridian dampness and heat of the function. The treatment of premature ejaculation needs to go to the hospital in a timely manner by a professional doctor to confirm the diagnosis, and then according to the patient’s own situation for the diagnosis and treatment, do not self-medication.