It is believed that vascular compression of the trigeminal nerve leads to local demyelination of the trigeminal nerve, resulting in ectopic impulses and the formation of pseudosynaptic or short-circuiting of adjacent axonal fibers, through which minor nociceptive stimuli are transmitted to the center, and the impulses generated by the center are also transmitted through the short-circuit, thus causing trigeminal neuralgia attacks by superposition. Gender and age The age of trigeminal neuralgia is mostly above 40 years old, with middle-aged and elderly people being the most common. The pain is more on the right side than on the left side. The pain starts from a point on the face, mouth or jaw and spreads to one or more branches of the trigeminal nerve, with the second and third branches being the most common. The pain does not extend beyond the midline of the face and does not exceed the area of distribution of the trigeminal nerve. Occasionally, there is bilateral trigeminal neuralgia, accounting for 3%; the nature of the pain, such as cutting, stabbing, tearing, burning or electric shock-like intense pain, is unbearable or even unbearable for ordinary people, and is called the “world’s first pain”; the pattern of pain The onset of trigeminal neuralgia is often without warning, while the pain attacks are generally regular. Each pain attack lasts only a few seconds to a few minutes and stops abruptly. At the beginning of the disease, the number of attacks is small and the interval is long, ranging from several minutes to several hours, but as the disease develops, the attacks become more frequent, the interval is shortened, and the pain becomes more intense. The pain attacks decrease at night. There are often triggering factors: talking, eating, washing face, shaving, brushing teeth and wind blowing can trigger painful attacks, resulting in the patient being depressed, acting cautiously, not even daring to wash face, brush teeth, eat and speak carefully for fear of causing an attack; trigger point The trigger point, also called “trigger point”, is often located at Upper lip, nose, gums, corners of the mouth, tongue, eyebrows, etc. Light touch or stimulation of trigger points can trigger painful episodes; expression and facial changes The painful side of the face may show spasms, i.e. “painful spasms”, frowning and clenching teeth, opening the mouth to cover the eyes, or rubbing the face with the palm of the hand to cause local skin roughness, thickening, loss of eyebrows, conjunctival congestion, lacrimation and salivation. Salivation. The expression is tense and anxious. The adverse effects are mainly drowsiness, dizziness, gastrointestinal discomfort and other side effects, which can be taken twice a day at the beginning and three times a day later. 0.2~0.6g per day, divided into 2~3 doses, and the maximum daily amount should not exceed 1.2g. Surgical treatment, mainly microvascular decompression, does not produce sensory and motor disorders while relieving pain, and is the safest and most effective method widely used at present.