According to China’s cosmetic health supervision regulations on the definition of cosmetics is: cosmetics are applied, sprayed or other similar methods, applied to any part of the human surface (skin, hair, nails, lips, etc.) to clean, eliminate bad odors, skin care, beauty and grooming purposes of daily use chemical industrial products. Cosmetics are classified as: cleaning agents, such as milk, soap, shampoo, toothpaste, bath soap, etc.; toners, such as eye shadow, lipstick, nail polish, hair dye, rouge, etc.; styling agents, such as hair styling agent; aromatic agents, such as perfume, deodorant, etc.; sunscreens, such as sunscreen, sunscreen oil, etc.; nutritional protection agents, such as moisturizers, nutritional creams, etc.; therapeutic cosmetics, such as deodorant, spot cream, etc.. Generally speaking, before any kind of formal cosmetics are marketed, they have to go through a series of product testing tests for safety and quality control. In recent years, as cosmetic manufacturers continue to pursue the functional effects of cosmetics and the growing demand of cosmetic consumers, the rate of cosmetic dermatitis in clinical outpatient clinics is just getting higher and higher. However, the actual situation in the country is that patients and most dermatologists are still not sufficiently aware of it, as evidenced by the fact that patients are often influenced by traditional Chinese medicine and traditional culture to first consider whether they have eaten something and developed “facial allergy”; while dermatologists are not conceptually clear and habitually confused. The diagnosis of “seborrheic dermatitis” results in a delayed condition and treatment! There are two types of cosmetic dermatitis, one is the cosmetic itself has problems; the other is the cosmetic itself is not a problem, but not suitable for the user. The main cause of contact dermatitis caused by cosmetics is the irritation of the cosmetics themselves or the user’s allergy to the fragrances, preservatives, lanolin, etc. Some cosmetics also contain heavy metals. Some cosmetics also contain heavy metals, such as creams containing mercury, which usually focus on “skin brightening” and “anti-aging”; lipsticks containing lead, which can cause skin pigmentation with long-term use. There are also cosmetics with various nutrients, such as proteins, vitamins, ginseng, etc., but they are prone to deterioration over time, and thus can have an irritating effect on the skin. Mascara, eyebrow dye oil with bacteria, eye bacteria can enter the cream through the brush of mascara; some hair products have been tested and found to contain formaldehyde ingredients, which is a carcinogen; foundations and powders contain a variety of minerals. In addition, there are quite a few substandard and poor quality cosmetics on the market (such as some so-called direct marketing cosmetics), which contain lead, mercury and other heavy metals that exceed the standard, or contain hormones, which can cause greater irritation and damage to the skin, at which time the skin may show varying degrees of erythema, edema, itching, papules, etc., and in severe cases, blistering erosion. Our literature reports found that the type of cosmetics that cause cosmetic dermatitis, the most common is the skin care category, including moisturizing creams, nutritional creams, etc.; followed by the skin cleansing category including facial cleansers, soaps, shampoos, baths, etc.; and foundation, lipstick, eye shadow, etc. are not uncommon. The results of the patch test with standard antigen series: the most positive reactions are fragrances and preservatives, in line with foreign reports. The spices are specifically referred to as: spice I (jasmine flavor, new international flavor, tuberose A flavor), spice II (white rose flavor, lilac flavor, osmanthus flavor). Followed by preservatives:Mizunoalkyl urea, paraben, brombol, formaldehyde; in addition: p-phenylenediamine, nickel sulfate, rosin. The above antigens are related to the production components of cosmetics, of which one of the antigens is positive, i.e., clinically all may cause cosmetic dermatitis. Therefore, for cosmetic dermatitis that is highly suspected clinically, it is best to perform a patch test of the standard antigen series in addition to the patch test with the cosmetic original. Cosmetics have an irreplaceable role in beautifying people’s lives, while preservatives, fragrances and antibacterial agents in cosmetics can also cause a wide variety of skin damage. Therefore, people are concerned about the effect of cosmetics on skin care and beauty at the same time a, more attention should be paid to the safety of cosmetics. The key to preventing cosmetic dermatitis is to indicate the ingredients on the cosmetic label. Once the possible allergenic substances have been identified in patients who have developed cosmetic dermatitis, it only makes sense to know which cosmetics have these substances. Therefore, prompting cosmetic manufacturers to move towards standardization and maturity to ensure the safety of cosmetic use will be more conducive to rational consumer consumption and rational selection of skin care products that suit their needs.