When it comes to hyaluronic acid, most people are not unfamiliar with it, and hyaluronic acid injection is a relatively safe plastic surgery method. However, few people have heard of the size of hyaluronic acid molecules, in fact, there is a difference between hyaluronic acid molecules, so what is the difference between large and small molecules of hyaluronic acid? As a commonly used injectable filling material, hyaluronic acid is widely used for filling and wrinkle removal and shaping, and has been favored by many beauty lovers. Hyaluronic acid can be divided into large-molecule hyaluronic acid, medium-molecule hyaluronic acid and small-molecule hyaluronic acid according to the size of the molecule, and the role of different molecule size hyaluronic acid is also different. What is the difference between large-molecule, medium-molecule and small-molecule hyaluronic acid? Large molecule hyaluronic acid has the function of filling and shaping, which is mainly used in shaping procedures such as breast augmentation and buttock augmentation, nose augmentation and chin augmentation, etc. The filling area is deep tissue. Hyaluronic acid can also be used to remove wrinkles. Hyaluronic acid is injected in the form of filler into the dermal folds and depressions or areas that want to be plumped up, such as lips, cheeks, chin, etc. The effect of using large molecule hyaluronic acid can be maintained for a longer period of time. Medium-molecule hyaluronic acid is usually used to remove wrinkles, and the injection sites are usually tear troughs, lips and wrinkles, and it also has the function of filling depressions. Small molecule hyaluronic acid is a water-like hyaluronic acid molecule, which is mainly used for injection into the dermis of the whole face to replenish the missing water in the dermis, as well as to repair the damaged skin and play the role of moisturizing and rejuvenating the skin, making up for the shortage of large and medium molecule hyaluronic acid. It is undeniable that some people do microplastic injections very blindly, and after doing so, they do not even know what hyaluronic acid does. Various models have different requirements for facial plastic surgery sites, corresponding to different molecular sizes and maintenance durations, as well as different indications, so we must be very clear and use it correctly. The FDA approved Restylane has a variety of dosage forms: 1. Hyaluronic acid Restylane Touch: What is the role of the small molecule Restylane Touch hyaluronic acid? It is suitable for microplastic injections for fine lines around the eyes and all superficial fine lines on the face, tear trough lines, etc. It has a shorter maintenance time. 2. Restylane: Medium molecule Restylane is suitable for microplastic injections such as line lifting facial plastic surgery, head-lift lines, decal lines, lip augmentation. The maintenance time is about half a year. 3, Restylane Perlane hyaluronic acid: estylane Perlane hyaluronic acid belongs to the medium molecular structure, suitable for filling depressions, nasal sculpture, cheek augmentation, chin augmentation and other microplastic beauty. The maintenance time is about half a year long. 4.Restylane Vital Vital Hyaluronic Acid: What is the role of this vital hyaluronic acid, it is newly marketed in 2008, applicable to the neck, hands, knees, chest wrinkles revision role, but also as a way to tighten the skin, whitening and other cosmetic. 5, Restylane Lipp: Medium molecular structure, especially suitable for lip augmentation microplastic injection, lip lines, lifting the corners of the mouth and other facial plastic surgery. It is more stable than the previous ones and has a better stability. 6. Restylane SubQ hyaluronic acid: It belongs to the large molecular structure, suitable for filling large depressions and can modify the face shape. Due to the molecular structure, the stability is higher and the maintenance time is extended to about three years. 7. Macrolane hyaluronic acid: What is the role of the last type of hyaluronic acid? It is suitable for larger plastic surgery such as breast augmentation and buttock augmentation. Because the maintenance time can be up to one * five years, the trial rate of this type of hyaluronic acid is higher. The order in which hyaluronic acid is used is different for different models! This kind of microplastic injection is the principle that the larger molecule is injected first – first, the larger molecule of hyaluronic acid (PerlaneorSubQ) should be injected at a deeper location (near the periosteum), just like laying a foundation, and using a thicker, harder-textured object to hold up the body, and then using a smaller molecule of hyaluronic acid (Touch) to fill in the dermis near the surface of the dermis to produce a smooth surface. So it is said that cosmetic injections with hyaluronic acid can also tighten the skin and restore smoothness.