The causes of acne on the nose may include excessive sebum secretion, blockage of the sebaceous ducts of hair follicles, bacterial infection and inflammatory reactions. 1. Excessive sebum secretion: Usually after the patient enters puberty, the level of androgens in the body, especially testosterone, increases rapidly, which promotes the development of sebaceous glands and the production of a large amount of sebum, leading to the occurrence of acne. 2. Blockage of follicular sebaceous gland ducts: Abnormal keratinization of follicular sebaceous gland ducts can lead to blockage of the ducts, impaired sebum secretion, and the formation of keratin clogs, which in turn leads to acne. 3. Bacterial infection and inflammatory response: Various microorganisms in the hair follicle, especially Propionibacterium acnes, will proliferate. The lipase produced by Propionibacterium acnes will break down sebum to produce free fatty acids. At the same time it has a chemotactic effect on inflammatory cells and mediators, ultimately inducing and aggravating the inflammatory response. There are many other causes of acne on the nose, and it is recommended that patients go to the hospital in a timely manner to clarify the cause of the disease, and then standardize the treatment under the guidance of the doctor to avoid serious conditions.