The main drugs for the treatment of gout first attack in young people include colchicine, non-steroidal anti-inflammatory drugs and uric acid-lowering drugs. 1. Colchicine: Colchicine can inhibit phospholipase A2, interleukin-6 and bind with neutrophil subunits to relieve the pain symptoms of acute gout attack, but it should be noted that patients taking colchicine treatment should be regularly tested for blood counts and liver and kidney functions. 2. Non-steroidal anti-inflammatory drugs: non-steroidal anti-inflammatory drugs can be used in the treatment of acute attacks of gout in order to alleviate the symptoms of patients, common non-steroidal anti-inflammatory drugs include ibuprofen, etoricoxib and so on, the use of non-steroidal anti-inflammatory drugs during the treatment of gastrointestinal tract ulcers, hemorrhage and other diseases should be wary of the occurrence of. 3. Uric acid-lowering drugs: common uric acid-lowering drugs include allopurinol, benzbromarone, febuxostat, etc., which can inhibit the production of uric acid or promote the excretion of uric acid to play a role in lowering the level of uric acid in the patient’s body, and the patient should drink as much water as possible during the period of taking the drug. It is recommended that young patients with first attacks of gout go to the rheumatology and immunology departments of regular hospitals and other related departments for consultation, and follow the doctor’s instructions to take medication, do not take medication on their own.